Meaning
What does PepeHands mean?
PepeHands is a emote created for the streaming website Twitch.tv, featuring the character Pepe the Frog holding his hands up and in some cases with tears running down his face.
The emote is a variant of the original emote FeelsGoodMan and is used to express discomfort/sadness, literally like when someone is saying: “Why god, why?”.
PepeHands is part of the emotes which were based on Pepe the Frog as following:
Origin
What's the origin of PepeHands?
Originates from the streaming website Twitch.tv, where it can be posted when using the FrankerFaceZ extension for your browser, which enhances your stream viewing experience with content like new and unique emotes, chat feature, etc.
PepeHands was added to the FrankerFaceZ collection in late 2016.
Spread & Usage
How did PepeHands spread?
Almost a year after its debut to FrankerFaceZ, PepeHands became popular amongst the viewers and fans of streamer Forsen.
People used the emote to express their sadness due to the shift in style he has went through after in 2017. thus popularising the use of the emote as it was spammed on his channel for a long period of time. As of 10/12/2019, PepeHands is 33rd on the top 100 most used emotes list according to the website StreamElements.

External resources
- Know Your Meme – Pepehands